Hong Zhou

by Hong Zhou
VP of Product & AI Innovation
KnowledgeWorks Global Ltd. 

LinkedIn

Key takeaways

  • AI should improve the quality of evidence behind peer-review decisions, not simply make peer review faster. The goal is to strengthen editorial judgment while preserving human accountability.
  • Quality assurance can move earlier in the publishing workflow. AI-assisted checks during manuscript preparation, submission, and triage can resolve reporting gaps and technical issues before they consume reviewer attention.
  • AI-assisted peer review requires transparent human oversight. Editors need to understand automated flags, review supporting evidence, challenge outputs, and know when issues should be escalated.
  • “Executable peer review” could extend assessment beyond the manuscript itself. For suitable computational research, AI agents may help reconstruct software environments, run code, compare outputs, and provide additional evidence for reviewers.
  • Publishers should evaluate AI-assisted peer review using evidence, not turnaround time alone. Useful measures include resolved omissions, useful findings, missed issues, total effort and cost, and successful completion of computational checks.
  • The long-term opportunity is a human–AI trust architecture across the publishing lifecycle. Evidence, accountability, and opportunities for correction should remain connected from submission and review through publication and post-publication processes.

A faster peer-review process is not necessarily a better one. We can shorten turnaround times and generate more review text without improving the decisions that shape the scholarly record. For me, that is the central challenge in applying AI to peer review: are we accelerating the existing process, or strengthening the evidence behind editorial judgment?

Peer review is an essential layer of scholarly trust, not a certification that research is correct or reproducible. Its limitations should prompt us to rethink where assurance happens, what reviewers should contribute, and how responsibility continues after publication.

Protect the judgment we cannot automate 

The conversation about reviewer capacity often starts with recruiting more reviewers. I believe we should first ask how much avoidable work reaches those we already have. Missing reporting information, incomplete references, unavailable data, and unresolved technical issues can distract from the assessment that requires disciplinary expertise. Increasing capacity should mean protecting attention, not simply increasing the number of completed reviews. 

This is why quality assurance needs to move upstream. AI-assisted checks could help authors address problems during manuscript preparation and support editorial teams during submission and triage. Reviewers could then devote more attention to methodology, interpretation, originality, and significance. The objective should not be to help experts produce review text faster, but to help them review more deeply. 

From a product perspective, this argues for an adaptive workflow rather than a standard checklist applied indiscriminately. A clinical trial, a computational study, and a humanities article should not trigger identical checks. The system should surface evidence relevant to the manuscript and make clear which questions remain unresolved. 

Randomized trial, PLOS ONE, 2019
Evidence from reporting-guideline interventions shows why implementation matters. In a randomized trial at PLOS ONE published in 2019, requesting an ARRIVE reporting checklist without verifying its contents did not improve full compliance in accepted animal-research papers.
Moving checks earlier only helps if their outputs are useful. Otherwise, we risk replacing reviewer fatigue with editorial alert fatigue.

Make responsibility part of the design

As I discussed in my earlier article on AI in peer review, AI speed must remain paired with human judgment. The practical question is how that principle shapes the evidence editors receive and the authority they have to act on it.

Putting that principle into practice requires more than a human approval button. Editors need to understand what a flag means, examine the supporting evidence, challenge an output, and know when to escalate. As AI systems gain autonomy, governance should become stronger and more visible.

For reviewers, LOCAD (Limitations, Ownership, Confidentiality, Accuracy, and Disclosure) remains a practical reminder of the responsibilities that accompany AI assistance.

L
Limitations
O
Ownership
C
Confidentiality
A
Accuracy
D
Disclosure

An automated signal should initiate scrutiny, not substitute for a verdict. Accountability must remain identifiable throughout the workflow.

Move from checking manuscripts to testing research

The longer-term opportunity is to examine more of the research behind the manuscript. Checking whether a data-availability statement exists is useful. Establishing whether the underlying analysis supports the reported results is a different level of assurance.

I see an emerging direction toward “executable peer review.” For suitable computational research, AI agents could help reconstruct software environments, run code, compare outputs, and support checks of important assumptions identified by reviewers. These activities could give reviewers evidence that would otherwise be difficult or time-consuming to obtain. This is a direction to develop, not a capability to assume across every discipline.

Precedent: American Economic Association
The American Economic Association offers a practical precedent: its data-editor team checks research materials, documents reproducibility problems and asks authors to resolve outstanding issues before final acceptance. A publisher exploring AI assistance could build on that model, linking each finding to supporting evidence, a clear author query and a recorded resolution.

Successful execution would not remove the need for scientific judgment or establish that the underlying research is valid. Reviewers would still need to assess whether the methods are appropriate, the assumptions defensible, and the conclusions warranted. More machine-generated evidence should enable deeper human assessment, not create another automatic approval signal.

Randomized study, PNAS, 2026
A randomized study published in PNAS in 2026 assigned 288 researchers to teams assessing the reproducibility of quantitative social-science research. Teams using AI assistance and those working without AI achieved similar reproduction rates, but the latter detected more major coding errors. The finding is specific to the study’s tasks and tools, and reinforces the need to measure what an AI-assisted workflow misses.
Five measures for the pilot
I would begin with one journal and a defined group of suitable computational submissions, with agreed checks, appropriate author permissions, and a named editorial owner. Comparing similar submissions under the current and AI-assisted workflows, with random allocation where feasible, would help establish what changes. The measures and criteria for expansion should be agreed before the pilot begins.
Alongside turnaround time, I would assess the pilot against five practical measures:
Resolved omissions
The proportion of confirmed reporting gaps addressed before review, or technical questions resolved before the relevant editorial decision.
Useful findings
The proportion of flags that editors or subject experts confirm warrant action, with documentation gaps distinguished from issues affecting results.
Missed issues
Problems found through independent expert assessment of a sample of manuscripts, including those that received no flag.
Total effort and cost
Staff and reviewer time, author follow-up, technical support, and tool costs per manuscript.
Check completion
The proportions of computational checks that reproduce reported outputs, reveal discrepancies, or remain inconclusive.

Expansion should depend on whether the evidence helps editors make better-supported decisions at a proportionate cost. A ten-minute review is not progress if it produces a weaker decision.

For KGL and the publishers and societies we support, this is a content-lifecycle question, not just an editorial technology question. Evidence and responsibility should remain connected across submission, review, production, digital delivery, and post-publication correction. Publication should not mark the end of assurance.

The opportunity is therefore larger than automating yesterday’s workflow. It is to build a human–AI trust architecture that protects scarce expertise, makes decisions more accountable, and remains open to correction.

The question worth asking is not simply, “How quickly can we complete peer review?” It is, “How much more confidence can the process earn?”

Dr. Hong Zhou is Vice President, Product Management at KGL, where he leads product strategy and AI innovation for solutions serving researchers, librarians, and publishers. He can be reached at info@kwglobal.com.

Go to Top